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KMID : 0928520070170010001
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Korean Journal of Lipidology
2007 Volume.17 No. 1 p.1 ~ p.10
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The Family History of Cardiovascular Risk Factors as a Predictor of Metabolic Syndrome among Adults
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Jang Shin-Yi
Joo Eun-Young
Cho Sung-Il
Lee Seung-Wook
Kim Duk-Kyung
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Abstract
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Objective: The aim of this study is to predict occurrence of metabolic syndrome when a family history (FHx) of hypertension/cerebrovascular accident, cardiovascular disease, and/or type 2 diabetes is positive.
Methods: The sample included 5,742 Korean men and women aged 20 years or older. A numeric score 1 was assigned to each of positive family histories. Scores were summed ranging from zero to three.
Results: People of the group with metabolic syndrome were of older age, with relatively low education, and in relatively low economic level compared to the people of the group without metabolic syndrome. This group also showed higher ratio of females and higher score of FHx of cardiovascular risk factors (FHx scores). After age, gender and socioeconomic position (SEP) were adjusted, the odds ratios (OR) of FHx scores for metabolic syndrome were 1.47 (95% CI 1.27~1.71, P<0.001), 1.54 (95% CI 1.13~2.09, P<0.01) and 3.98 (95% CI 1.33~11.9 P<0.05) for the numeric scores one, two, and three, respectively. The adjusted OR of the age group less than 50-year-old was higher than that of the age group 50-year-old or older. For the age group less than 50-year-old, positive predictability of the FHx scores for metabolic syndrome was 66% (sensitivity 65%, specificity 61%) after adjustment of age, gender and SEP. For the age group 50-year-old or older, positive predictability was 53% (sensitivity 62%, specificity 60%).
Conclusions: This study suggests that the subject who has a higher FHx scores may have higher risk for metabolic syndrome.
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KEYWORD
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Cardiovascular Disease, Causality, Metabolic Syndrome X, Predisposing Factor, Risk Factors
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